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CFDE Workbench

PNMT (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:ENTREZ:5409, HGNC:9160, MIM:171190, NM_002686, NP_002677, NR_073461, PENT, PNMT, PNMTase, XM_011524909, XP_011523211, phenylethanolamine N-methyltransferase
Omim:OMIM:171190
Id:ENSG00000141744
Hgnc:HGNC:9160
Entrez:5409
Ensembl:ENSG00000141744
Description:phenylethanolamine N-methyltransferase
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012]

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Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PNMT's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PNMT.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PNMT.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PNMT.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PNMT.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE152699 GSE152723 vemurafenib 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE201309 matrine 5 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE239844 crizotinib 7 v 10 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE201309 matrine 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE160349 IDAM T cell 1 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE103122 puromycin 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE207410 GSE207411 ARID1A knockdown 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE164874 prednisolone muscle organ 5 v 10 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE146888 prostaglandin H28834 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE216274 GSE216292 palbociclib 4 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE152699 GSE152723 vemurafenib 0 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE201309 matrine 5 v 3 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE239844 crizotinib 7 v 10 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE201309 matrine 1 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE160349 IDAM T cell 1 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE103122 puromycin 0 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE207410 GSE207411 ARID1A knockdown 2 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE164874 prednisolone muscle organ 5 v 10 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE146888 prostaglandin H28834 0 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE216274 GSE216292 palbociclib 4 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

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    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.