PDGFRA (Gene)

Entrez Gene ID: 5156

Description: platelet derived growth factor receptor alpha

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PDGFRA's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PDGFRA.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PDGFRA.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PDGFRA.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PDGFRA.

Gene Sets (2479)

LINCS L1000 Chem Pert Consensus Sigs (1225)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (1227)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (4)

A gene set library provided by GTEx

IDG Drug Targets 2022 (20)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
GANGALEOIDIN Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PDGFRA Gene (Entity type)	0.021017252
SA-1920013 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PDGFRA Gene (Entity type)	0.008590033
Neomycin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PDGFRA Gene (Entity type)	0.021785423
phenprobamate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PDGFRA Gene (Entity type)	-0.011015988
N-{4-chloro-2-hydroxy-3-[(3S)-3-piperidinylsulfonyl]phenyl}-N'-(3-fluoro-2-methylphenyl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PDGFRA Gene (Entity type)	0.0056443345
n-methylphenothiazine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PDGFRA Gene (Entity type)	-0.014740206
Tolcapone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PDGFRA Gene (Entity type)	0.0059953905
valyltryptophan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PDGFRA Gene (Entity type)	0.012005496
allantoxanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PDGFRA Gene (Entity type)	-0.026226653
mead-ethanolamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PDGFRA Gene (Entity type)	0.008061221

GANGALEOIDIN
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PDGFRA
Gene (Entity type)
0.021017252

SA-1920013
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PDGFRA
Gene (Entity type)
0.008590033

Neomycin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PDGFRA
Gene (Entity type)
0.021785423

phenprobamate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PDGFRA
Gene (Entity type)
-0.011015988

N-{4-chloro-2-hydroxy-3-[(3S)-3-piperidinylsulfonyl]phenyl}-N'-(3-fluoro-2-methylphenyl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PDGFRA
Gene (Entity type)
0.0056443345

n-methylphenothiazine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PDGFRA
Gene (Entity type)
-0.014740206

Tolcapone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PDGFRA
Gene (Entity type)
0.0059953905

valyltryptophan
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PDGFRA
Gene (Entity type)
0.012005496

allantoxanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PDGFRA
Gene (Entity type)
-0.026226653

mead-ethanolamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PDGFRA
Gene (Entity type)
0.008061221

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.