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CFDE Workbench

EDEM1 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:EDEM, EDEM1, ENTREZ:9695, ER degradation enhancing alpha-mannosidase like protein 1, HGNC:18967, MIM:607673, NM_014674, NP_055489, XM_011534271, XM_011534272, XP_011532573, XP_011532574, XR_001740383, XR_001740384
Omim:OMIM:607673
Id:ENSG00000134109
Hgnc:HGNC:18967
Entrez:9695
Ensembl:ENSG00000134109
Description:ER degradation enhancing alpha-mannosidase like protein 1
Enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity and misfolded protein binding activity. Involved in mannose trimming involved in glycoprotein ERAD pathway; positive regulation of retrograde protein transport, ER to cytosol; and protein targeting to ER. Located in aggresome and endoplasmic reticulum quality control compartment. [provided by Alliance of Genome Resources, Apr 2022]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View EDEM1's neighborhood in the knowledge graph.

Submit
Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with EDEM1.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using EDEM1.

Submit
Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for EDEM1.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with EDEM1.

Results found

Linked to

 

Label

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Gene Set (Entity type)

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GSE199859 A-7 HCA7 1 v 2 human up

Gene Set (Entity type)

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GSE193993 SSTR2 knockout 4 v 7 human up

Gene Set (Entity type)

A Gene Set from LINCS

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GSE110709 GSK-J4 5 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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GSE193993 SSTR2 knockout 1 v 7 human up

Gene Set (Entity type)

A Gene Set from LINCS

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GSE118816 Myo1c knockdown podocyte 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE179112 GSE179113 hydroxyl Hutt45 4 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE233647 docetaxel UFERSA-PC3 DU145 4 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE193993 SSTR2 knockout 0 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE99875 everolimus 2 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE176008 pyridoxine 4 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE199859 A-7 HCA7 1 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE193993 SSTR2 knockout 4 v 7 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE110709 GSK-J4 5 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE193993 SSTR2 knockout 1 v 7 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE118816 Myo1c knockdown podocyte 0 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
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