PXDN (Gene)

Entrez Gene ID: 7837

Description: peroxidasin

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PXDN's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PXDN.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PXDN.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PXDN.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PXDN.

Gene Sets (4718)

LINCS L1000 Chem Pert Consensus Sigs (892)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (5)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (27)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (4)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (1082)

A gene set library provided by LINCS

rummageo gene perturbations (247)

A gene set library provided by LINCS

RummaGEO DrugPerturbations 2025 (807)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1251)

A gene set library provided by LINCS

rummageo chemical perturbations (399)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (3)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Tirapazamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PXDN Gene (Entity type)	-0.0047093406
LFM-A13 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PXDN Gene (Entity type)	-0.0041448777
PSH-026 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PXDN Gene (Entity type)	0.010951292
Guaiacol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PXDN Gene (Entity type)	-0.019421546
ranitidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PXDN Gene (Entity type)	-0.004400342
timonacic Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PXDN Gene (Entity type)	0.0040654005
Nicergoline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PXDN Gene (Entity type)	-0.003307719
VX-702 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PXDN Gene (Entity type)	-0.005793179
5-(4,4-dimethyl-2-thioxo-2,4-dihydro-1H-benzo[d][1,3]oxazin-6-yl)-1-methyl-1H-pyrrole-2-carbonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PXDN Gene (Entity type)	0.004214504
metrifonate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PXDN Gene (Entity type)	-0.012412377

Tirapazamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PXDN
Gene (Entity type)
-0.0047093406

LFM-A13
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PXDN
Gene (Entity type)
-0.0041448777

PSH-026
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PXDN
Gene (Entity type)
0.010951292

Guaiacol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PXDN
Gene (Entity type)
-0.019421546

ranitidine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PXDN
Gene (Entity type)
-0.004400342

timonacic
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PXDN
Gene (Entity type)
0.0040654005

Nicergoline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PXDN
Gene (Entity type)
-0.003307719

VX-702
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PXDN
Gene (Entity type)
-0.005793179

5-(4,4-dimethyl-2-thioxo-2,4-dihydro-1H-benzo[d][1,3]oxazin-6-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PXDN
Gene (Entity type)
0.004214504

metrifonate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PXDN
Gene (Entity type)
-0.012412377

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.