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CFDE Workbench

PARP2 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:ADPRT2, ADPRTL2, ADPRTL3, ARTD2, ENTREZ:10038, HGNC:272, MIM:607725, NM_001042618, NM_005484, NP_001036083, NP_005475, PARP-2, PARP2, XM_005267247, XM_017020912, XP_005267304, XP_016876401, pADPRT-2, poly(ADP-ribose) polymerase 2
Omim:OMIM:607725
Id:ENSG00000129484
Hgnc:HGNC:272
Entrez:10038
Ensembl:ENSG00000129484
Description:poly(ADP-ribose) polymerase 2
This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PARP2's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PARP2.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PARP2.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PARP2.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PARP2.

Results found

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Label

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A Gene Set from LINCS

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GSE213588 trametinib NF1 9 v 5 human dn

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A Gene Set from LINCS

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GSE161800 cisplatin A-549 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE163297 doxorubicin 0 v 2 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE252944 AKT inhibition 7 v 9 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE168602 GSE168604 selumetinib COLO205 2 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE133933 fibulin-3 knockdown 2 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE213588 trametinib NF1 8 v 7 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE182150 KIT LSD1 MYC inhibition 2 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE213588 trametinib NF1 8 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE133927 PTEN p53 Meox1 knockdown BT-549 RNA Small Interfering 1 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE213588 trametinib NF1 9 v 5 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE161800 cisplatin A-549 0 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
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    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
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