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CFDE Workbench

VPREB3 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:8HS20, ENTREZ:29802, HGNC:12710, MIM:605017, N27C7-2, NM_013378, NP_037510, V-set pre-B cell surrogate light chain 3, VPREB3
Omim:OMIM:605017
Id:ENSG00000128218
Hgnc:HGNC:12710
Entrez:29802
Ensembl:ENSG00000128218
Description:V-set pre-B cell surrogate light chain 3
The protein encoded by this gene is the human ortholog of the mouse VpreB3 (8HS20) protein, is thought to be involved in B-cell maturation, and may play a role in assembly of the pre-B cell receptor (pre-BCR). While the role of this protein in B-cell development has not yet been elucidated, studies with the chicken ortholog of this protein have found that when overexpressed, this protein localizes to the endoplasmic reticulum. The mouse ortholog of this protein has been shown to associate with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. Expression of this gene has been observed in some lymphomas. [provided by RefSeq, Apr 2015]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View VPREB3's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with VPREB3.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using VPREB3.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for VPREB3.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with VPREB3.

Results found

Linked to

 

Label

Description

 

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GSE120612 7 V 2 ETOPOSIDE HUMAN DN

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A Gene Set from LINCS

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GSE176366 vincristine 0 v 1 human dn

Gene Set (Entity type)

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GSE116810 5 V 4 SELINEXOR HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

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GSE176403 GSE176404 LSD1 inhibition 1 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

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GSE165548 gemcitabine 2 v 13 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE236437 0 V 3 ALDOSTERONE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE115384 CELSR2 knockdown 5 v 7 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE115384 CELSR2 knockdown 0 v 7 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE120612 etoposide leukocyte 7 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE120612 etoposide leukocyte 7 v 2 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE120612 7 V 2 ETOPOSIDE HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE176366 vincristine 0 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE116810 5 V 4 SELINEXOR HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE176403 GSE176404 LSD1 inhibition 1 v 3 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE165548 gemcitabine 2 v 13 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE236437 0 V 3 ALDOSTERONE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE115384 CELSR2 knockdown 5 v 7 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE115384 CELSR2 knockdown 0 v 7 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE120612 etoposide leukocyte 7 v 5 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

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    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.