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CFDE Workbench

TNFSF14 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:CD258, ENTREZ:8740, HGNC:11930, HVEML, LIGHT, LTg, MIM:604520, NM_001376887, NM_003807, NM_172014, NP_001363816, NP_003798, NP_742011, TNF superfamily member 14, TNFSF14, XM_017027418, XP_016882907, XR_001753777, XR_936212
Omim:OMIM:604520
Id:ENSG00000125735
Hgnc:HGNC:11930
Entrez:8740
Ensembl:ENSG00000125735
Description:TNF superfamily member 14
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

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Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TNFSF14's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with TNFSF14.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TNFSF14.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TNFSF14.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TNFSF14.

Results found

Linked to

 

Label

Description

 

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GSE235390 4 V 0 LURBINECTEDIN HUMAN DN

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GSE147662 3 V 5 NICOTINAMIDE MOUSE UP

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GSE137325 copanlisib Hair-M 2 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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GSE191005 ENL knockout MOLM-13 1 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

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GSE129698 SYK inhibition 3 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE199204 GSE211619 glutamine 4 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE129698 SYK inhibition 6 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE183141 trichloroethylene macrophage 5 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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GSE103510 STAT5 inhibition 2 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE235390 4 V 0 LURBINECTEDIN HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE214306 CCM1 knockout 5 v 2 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE147662 3 V 5 NICOTINAMIDE MOUSE UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE137325 copanlisib Hair-M 2 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE191005 ENL knockout MOLM-13 1 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE129698 SYK inhibition 3 v 4 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE199204 GSE211619 glutamine 4 v 6 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE129698 SYK inhibition 6 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE183141 trichloroethylene macrophage 5 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE103510 STAT5 inhibition 2 v 3 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

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    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
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