ADGRL2 (Gene)

Entrez Gene ID: 23266

Description: adhesion G protein-coupled receptor L2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ADGRL2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with ADGRL2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ADGRL2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ADGRL2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ADGRL2.

Gene Sets (3636)

LINCS L1000 Chem Pert Consensus Sigs (764)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (4)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (3)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (796)

A gene set library provided by LINCS

rummageo gene perturbations (208)

A gene set library provided by LINCS

RummaGEO DrugPerturbations 2025 (463)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1052)

A gene set library provided by LINCS

rummageo chemical perturbations (334)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (11)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
(5S,6S,9R)-5-Amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-Oxo-2,3-dihydro-1H-imidazo-[4,5-b]pyridin-1-yl)piperidine-1-carboxylate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADGRL2 Gene (Entity type)	0.0031870187
MW-SHH-97 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADGRL2 Gene (Entity type)	0.0038473117
thioctic-acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADGRL2 Gene (Entity type)	-0.0055226088
Tasisulam Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADGRL2 Gene (Entity type)	0.0050205286
SA-1456195 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADGRL2 Gene (Entity type)	0.008366165
Fenticonazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADGRL2 Gene (Entity type)	0.005403555
Estriol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADGRL2 Gene (Entity type)	0.003354078
Indapamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADGRL2 Gene (Entity type)	-0.0032236285
SA-1459234 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADGRL2 Gene (Entity type)	0.009330193
lysylphenylalanyl-tyrosine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADGRL2 Gene (Entity type)	0.011820703

(5S,6S,9R)-5-Amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-Oxo-2,3-dihydro-1H-imidazo-[4,5-b]pyridin-1-yl)piperidine-1-carboxylate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADGRL2
Gene (Entity type)
0.0031870187

MW-SHH-97
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADGRL2
Gene (Entity type)
0.0038473117

thioctic-acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ADGRL2
Gene (Entity type)
-0.0055226088

Tasisulam
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADGRL2
Gene (Entity type)
0.0050205286

SA-1456195
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADGRL2
Gene (Entity type)
0.008366165

Fenticonazole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADGRL2
Gene (Entity type)
0.005403555

Estriol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADGRL2
Gene (Entity type)
0.003354078

Indapamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ADGRL2
Gene (Entity type)
-0.0032236285

SA-1459234
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADGRL2
Gene (Entity type)
0.009330193

lysylphenylalanyl-tyrosine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADGRL2
Gene (Entity type)
0.011820703

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.