PHACTR1 (Gene)

Organism:

Homo sapiens

Synonyms:DEE70, EIEE70, ENTREZ:221692, HGNC:20990, MIM:608723, NM_001242648, NM_001322308, NM_001322309, NM_001322310, NM_001322311, NM_001322312, NM_001322313, NM_001322314, NM_001374581, NM_001374582, NM_001374583, NM_001374584, NM_030948, NP_001229577, NP_001309237, NP_001309238, NP_001309239, NP_001309240, NP_001309241, NP_001309242, NP_001309243, NP_001361510, NP_001361511, NP_001361512, NP_001361513, NP_112210, PHACTR1, RPEL, RPEL1, XM_005248934, XM_017010452, XM_017010454, XM_017010455, XM_017010456, XM_017010457, XM_017010458, XM_017010459, XM_017010460, XM_017010462, XM_017010464, XM_017010465, XM_017010466, XM_017010469, XP_005248991, XP_016865941, XP_016865943, XP_016865944, XP_016865945, XP_016865946, XP_016865947, XP_016865948, XP_016865949, XP_016865951, XP_016865953, XP_016865954, XP_016865955, XP_016865958, dJ257A7.2, phosphatase and actin regulator 1

Omim:OMIM:608723

Id:ENSG00000112137

Hgnc:HGNC:20990

Entrez:221692

Ensembl:ENSG00000112137

Description:phosphatase and actin regulator 1

The protein encoded by this gene is a member of the phosphatase and actin regulator family of proteins. This family member can bind actin and regulate the reorganization of the actin cytoskeleton. It plays a role in tubule formation and in endothelial cell survival. Polymorphisms in this gene are associated with susceptibility to myocardial infarction, coronary artery disease and cervical artery dissection. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PHACTR1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PHACTR1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PHACTR1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PHACTR1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PHACTR1.

Results found

Linked to

	Label	Description
	GSE120612 etoposide leukocyte 7 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE254526 GSE254528 MI-1 Kasumi-1 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE190937 AHCY MAT2A knockout Rael 4 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE120612 7 V 2 ETOPOSIDE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE119978 GSE180930 cisplatin 3 v 4 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE195503 progesterone 3 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE184892 trehalose fibroblast 4 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE235390 4 V 0 LURBINECTEDIN HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE176008 pyridoxine 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE158834 ADIPOR2 knockout HEK293 0 v 9 human dn Gene Set (Entity type)	A Gene Set from LINCS

GSE120612 etoposide leukocyte 7 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE254526 GSE254528 MI-1 Kasumi-1 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE190937 AHCY MAT2A knockout Rael 4 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE120612 7 V 2 ETOPOSIDE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE119978 GSE180930 cisplatin 3 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE195503 progesterone 3 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE184892 trehalose fibroblast 4 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE235390 4 V 0 LURBINECTEDIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE176008 pyridoxine 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE158834 ADIPOR2 knockout HEK293 0 v 9 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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