TRIM2 (Gene)

Organism:

Homo sapiens

Synonyms:CMT2R, ENTREZ:23321, HGNC:15974, MIM:614141, NM_001130067, NM_001302692, NM_001302693, NM_001302694, NM_001351054, NM_001351055, NM_001351056, NM_001351057, NM_001375488, NM_001375489, NM_001375490, NM_001375491, NM_001375512, NM_001375513, NM_001375514, NM_001375515, NM_001375516, NM_001375517, NM_001375519, NM_001375520, NM_001375522, NM_001375523, NM_001375525, NM_015271, NP_001123539, NP_001289621, NP_001289622, NP_001289623, NP_001337983, NP_001337984, NP_001337985, NP_001337986, NP_001362417, NP_001362418, NP_001362419, NP_001362420, NP_001362441, NP_001362442, NP_001362443, NP_001362444, NP_001362445, NP_001362446, NP_001362448, NP_001362449, NP_001362451, NP_001362452, NP_001362454, NP_056086, RNF86, TRIM2, XM_006714157, XM_006714158, XM_006714160, XM_006714161, XM_006714162, XM_006714165, XM_011531795, XM_011531796, XM_017007943, XM_017007944, XM_017007946, XM_017007947, XM_017007948, XM_017007949, XM_017007950, XM_017007953, XM_017007955, XP_006714220, XP_006714221, XP_006714223, XP_006714224, XP_006714225, XP_006714228, XP_011530097, XP_011530098, XP_016863432, XP_016863433, XP_016863435, XP_016863436, XP_016863437, XP_016863438, XP_016863439, XP_016863442, XP_016863444, tripartite motif containing 2

Omim:OMIM:614141

Id:ENSG00000109654

Hgnc:HGNC:15974

Entrez:23321

Ensembl:ENSG00000109654

Description:tripartite motif containing 2

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TRIM2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with TRIM2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TRIM2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TRIM2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TRIM2.

Results found

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	GSE89154 1 V 3 PROSCILLARIDIN HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE193993 SSTR2 knockout 4 v 7 human up Gene Set (Entity type)	A Gene Set from LINCS
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	GSE118816 Myo1c knockdown podocyte 0 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE261563 CX-5461 7 v 4 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE236280 panobinostat 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
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