ASPA (Gene)

Entrez Gene ID: 443

Description: aspartoacylase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ASPA's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with ASPA.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ASPA.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ASPA.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ASPA.

Gene Sets (1000)

LINCS L1000 Chem Pert Consensus Sigs (251)

A gene set library provided by LINCS

Metabolomics Workbench Metabolites 2022 (3)

A gene set library provided by MW

ARCHS4 IDG Coexp (32)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (16)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (206)

A gene set library provided by LINCS

rummageo gene perturbations (15)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (5)

A gene set library provided by GTEx

RummaGEO DrugPerturbations 2025 (121)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (307)

A gene set library provided by LINCS

rummageo chemical perturbations (36)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (5)

A gene set library provided by GTEx

IDG Drug Targets 2022 (1)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
ASPA Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Acetic Acid Metabolite (Entity type)
ASPA Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	N-Formyl-aspartic acid Metabolite (Entity type)
ASPA Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	N-acetylaspartic acid Metabolite (Entity type)
ASPA Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	formic acid Metabolite (Entity type)
SA-427604 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ASPA Gene (Entity type)	0.013402295
KFGENEBIN:ASPA-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	ASPA Gene (Entity type)
ASPA Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Aspartic Acid Metabolite (Entity type)
ASPA Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	acetic acid Metabolite (Entity type)
ASPA Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	aspartic acid Metabolite (Entity type)
SB-525334 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ASPA Gene (Entity type)	0.004241607

ASPA
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
Acetic Acid
Metabolite (Entity type)

ASPA
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
N-Formyl-aspartic acid
Metabolite (Entity type)

ASPA
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
N-acetylaspartic acid
Metabolite (Entity type)

ASPA
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
formic acid
Metabolite (Entity type)

SA-427604
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ASPA
Gene (Entity type)
0.013402295

KFGENEBIN:ASPA-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
ASPA
Gene (Entity type)

ASPA
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
Aspartic Acid
Metabolite (Entity type)

ASPA
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
acetic acid
Metabolite (Entity type)

ASPA
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
aspartic acid
Metabolite (Entity type)

SB-525334
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ASPA
Gene (Entity type)
0.004241607

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.