GPI (Gene)

Entrez Gene ID: 2821

Description: glucose-6-phosphate isomerase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View GPI's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GPI.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using GPI.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for GPI.

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Gene Sets (2641)

LINCS L1000 Chem Pert Consensus Sigs (680)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (1)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (459)

A gene set library provided by LINCS

rummageo gene perturbations (228)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (874)

A gene set library provided by LINCS

rummageo chemical perturbations (395)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Aristolochic-acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GPI Gene (Entity type)	-0.008567466
Ripasudil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GPI Gene (Entity type)	0.004204538
PCA 4248 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GPI Gene (Entity type)	0.0039549214
JS-K Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GPI Gene (Entity type)	0.020101152
4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GPI Gene (Entity type)	-0.0052183038
VU-0415555-1 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GPI Gene (Entity type)	-0.010962761
SA-1458689 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GPI Gene (Entity type)	-0.010279207
SF-11 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GPI Gene (Entity type)	-0.011204193
(S)-2-Methyl-butyric acid (1S,7S,8S)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GPI Gene (Entity type)	-0.0063884966
2-(1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido)acetic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GPI Gene (Entity type)	0.0033140276

Aristolochic-acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GPI
Gene (Entity type)
-0.008567466

Ripasudil
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GPI
Gene (Entity type)
0.004204538

PCA 4248
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GPI
Gene (Entity type)
0.0039549214

JS-K
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GPI
Gene (Entity type)
0.020101152

4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GPI
Gene (Entity type)
-0.0052183038

VU-0415555-1
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GPI
Gene (Entity type)
-0.010962761

SA-1458689
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GPI
Gene (Entity type)
-0.010279207

SF-11
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GPI
Gene (Entity type)
-0.011204193

(S)-2-Methyl-butyric acid (1S,7S,8S)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GPI
Gene (Entity type)
-0.0063884966

2-(1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido)acetic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GPI
Gene (Entity type)
0.0033140276

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.