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CFDE Workbench

BIRC5 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:API4, BIRC5, ENTREZ:332, EPR-1, HGNC:593, MIM:603352, NM_001012270, NM_001012271, NM_001168, NP_001012270, NP_001012271, NP_001159, XR_243654, XR_934452, baculoviral IAP repeat containing 5
Omim:OMIM:603352
Id:ENSG00000089685
Hgnc:HGNC:593
Entrez:332
Ensembl:ENSG00000089685
Description:baculoviral IAP repeat containing 5
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View BIRC5's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with BIRC5.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using BIRC5.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for BIRC5.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with BIRC5.

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    A Gene Set from LINCS

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    Gene Set (Entity type)

    A Gene Set from LINCS

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    A Gene Set from LINCS

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    A Gene Set from LINCS

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    A Gene Set from LINCS

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    Gene Set (Entity type)

    A Gene Set from LINCS

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    Gene Set (Entity type)

    A Gene Set from LINCS

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    A Gene Set from LINCS

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    Gene Set (Entity type)

    A Gene Set from LINCS

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    GSE254526 GSE254528 MI-1 Kasumi-1 0 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
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    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
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