FCN1 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)

Synonyms:ENTREZ:2219, FCN1, FCNM, HGNC:3623, MIM:601252, NM_002003, NP_001994, ficolin 1

Omim:OMIM:601252

Id:ENSG00000085265

Hgnc:HGNC:3623

Entrez:2219

Ensembl:ENSG00000085265

Description:ficolin 1

The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View FCN1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with FCN1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using FCN1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for FCN1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with FCN1.

Results found

Linked to

	Label	Description
	GSE114492 GSE153671 KMT2D inhibition 2 v 11 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE201309 matrine 1 v 6 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE119978 GSE180930 cisplatin 3 v 5 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE120612 etoposide leukocyte 7 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE201309 1 V 6 MATRINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE119978,GSE180930 3 V 5 CISPLATIN HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE196035 GSE196037 MEN1 inhibition 8 v 11 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE182150 KIT LSD1 MYC inhibition 6 v 7 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE216043 cisplatin 10 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE120612 7 V 3 ETOPOSIDE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS

GSE114492 GSE153671 KMT2D inhibition 2 v 11 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE201309 matrine 1 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE119978 GSE180930 cisplatin 3 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE120612 etoposide leukocyte 7 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE201309 1 V 6 MATRINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE119978,GSE180930 3 V 5 CISPLATIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE196035 GSE196037 MEN1 inhibition 8 v 11 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE182150 KIT LSD1 MYC inhibition 6 v 7 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE216043 cisplatin 10 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE120612 7 V 3 ETOPOSIDE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.