MCAM (Gene)

Entrez Gene ID: 4162

Description: melanoma cell adhesion molecule

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MCAM's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with MCAM.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MCAM.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MCAM.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MCAM.

Gene Sets (3472)

LINCS L1000 Chem Pert Consensus Sigs (677)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (1)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (3)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (558)

A gene set library provided by LINCS

rummageo gene perturbations (253)

A gene set library provided by LINCS

RummaGEO DrugPerturbations 2025 (581)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (932)

A gene set library provided by LINCS

rummageo chemical perturbations (444)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (16)

A gene set library provided by GTEx

HuBMAP ASCT-B (3)

A gene set library provided by HuBMAP

Knowledge Graph Assertions

Source	Relation	Target	Evidence
EBPC Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MCAM Gene (Entity type)	0.0049106586
bromocriptine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MCAM Gene (Entity type)	-0.0028930153
SA-1922932 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MCAM Gene (Entity type)	0.010268878
nisoxetine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MCAM Gene (Entity type)	-0.003534093
KU-C103654 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MCAM Gene (Entity type)	0.010427733
salsolidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MCAM Gene (Entity type)	0.018479917
10,10-bis((2-fluoropyridin-4-yl)methyl)anthracen-9(10H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MCAM Gene (Entity type)	0.0032980852
lonafarnib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MCAM Gene (Entity type)	0.003537908
SA-1922006 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MCAM Gene (Entity type)	0.013436329
SGX-523 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MCAM Gene (Entity type)	0.0026729875

EBPC
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MCAM
Gene (Entity type)
0.0049106586

bromocriptine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MCAM
Gene (Entity type)
-0.0028930153

SA-1922932
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MCAM
Gene (Entity type)
0.010268878

nisoxetine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MCAM
Gene (Entity type)
-0.003534093

KU-C103654
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MCAM
Gene (Entity type)
0.010427733

salsolidine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MCAM
Gene (Entity type)
0.018479917

10,10-bis((2-fluoropyridin-4-yl)methyl)anthracen-9(10H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MCAM
Gene (Entity type)
0.0032980852

lonafarnib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MCAM
Gene (Entity type)
0.003537908

SA-1922006
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MCAM
Gene (Entity type)
0.013436329

SGX-523
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MCAM
Gene (Entity type)
0.0026729875

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.