FSCN1 (Gene)

Entrez Gene ID: 6624

Description: fascin actin-bundling protein 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View FSCN1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with FSCN1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using FSCN1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for FSCN1.

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Gene Sets (2122)

LINCS L1000 Chem Pert Consensus Sigs (478)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (5)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (4)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (402)

A gene set library provided by LINCS

rummageo gene perturbations (256)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (1)

A gene set library provided by GTEx

LINCS L1000 Consensus Median Signatures (579)

A gene set library provided by LINCS

rummageo chemical perturbations (396)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SA-1920756 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FSCN1 Gene (Entity type)	-0.016862176
2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine(clothiapine)::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine::CHEMBL304902::Clothiapine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FSCN1 Gene (Entity type)	0.025710905
KFGENEBIN:FSCN1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	FSCN1 Gene (Entity type)
PSH-028 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FSCN1 Gene (Entity type)	0.012837413
Flumequine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FSCN1 Gene (Entity type)	-0.0154141225
Garcinol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FSCN1 Gene (Entity type)	0.004136313
SA-1459173 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FSCN1 Gene (Entity type)	-0.0103755705
hypericin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FSCN1 Gene (Entity type)	0.0055695632
VU-0415108-1 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FSCN1 Gene (Entity type)	0.009207163
tebuthiuron Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FSCN1 Gene (Entity type)	0.007413834

SA-1920756
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FSCN1
Gene (Entity type)
-0.016862176

2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine(clothiapine)::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine::CHEMBL304902::Clothiapine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FSCN1
Gene (Entity type)
0.025710905

KFGENEBIN:FSCN1-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
FSCN1
Gene (Entity type)

PSH-028
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FSCN1
Gene (Entity type)
0.012837413

Flumequine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FSCN1
Gene (Entity type)
-0.0154141225

Garcinol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FSCN1
Gene (Entity type)
0.004136313

SA-1459173
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FSCN1
Gene (Entity type)
-0.0103755705

hypericin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FSCN1
Gene (Entity type)
0.0055695632

VU-0415108-1
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FSCN1
Gene (Entity type)
0.009207163

tebuthiuron
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FSCN1
Gene (Entity type)
0.007413834

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.