TP63 (Gene)

Entrez Gene ID: 8626

Description: tumor protein p63

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TP63's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with TP63.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TP63.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TP63.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TP63.

Gene Sets (1057)

LINCS L1000 Chem Pert Consensus Sigs (534)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (504)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (5)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (8)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
pterostilbene Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TP63 Gene (Entity type)	0.0058776774
rel-3-Caffeoylquinic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TP63 Gene (Entity type)	-0.0060525793
NU-6027 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TP63 Gene (Entity type)	0.010437798
9-(4-{4-[(4'-Trifluoromethyl-biphenyl-2-carbonyl)-amino]-piperidin-1-yl}-butyl)-9H-fluorene-9-carboxylic acid (2,2,2-trifluoro-ethyl)-amide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TP63 Gene (Entity type)	0.003615332
Tolperisone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TP63 Gene (Entity type)	-0.0046009677
NPK76-II-72-1 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TP63 Gene (Entity type)	-0.004298849
carprofen Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TP63 Gene (Entity type)	-0.004156653
4-acetamido-N-(2-amino-5-(thiophen-2-yl)phenyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TP63 Gene (Entity type)	-0.008299582
Teniposide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TP63 Gene (Entity type)	0.012950765
SA-1925610 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TP63 Gene (Entity type)	0.014412341

pterostilbene
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TP63
Gene (Entity type)
0.0058776774

rel-3-Caffeoylquinic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TP63
Gene (Entity type)
-0.0060525793

NU-6027
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TP63
Gene (Entity type)
0.010437798

9-(4-{4-[(4'-Trifluoromethyl-biphenyl-2-carbonyl)-amino]-piperidin-1-yl}-butyl)-9H-fluorene-9-carboxylic acid (2,2,2-trifluoro-ethyl)-amide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TP63
Gene (Entity type)
0.003615332

Tolperisone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TP63
Gene (Entity type)
-0.0046009677

NPK76-II-72-1
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TP63
Gene (Entity type)
-0.004298849

carprofen
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TP63
Gene (Entity type)
-0.004156653

4-acetamido-N-(2-amino-5-(thiophen-2-yl)phenyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TP63
Gene (Entity type)
-0.008299582

Teniposide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TP63
Gene (Entity type)
0.012950765

SA-1925610
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TP63
Gene (Entity type)
0.014412341

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.