PLA2G10 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:8399, GXPLA2, GXSPLA2, HGNC:9029, MIM:603603, NM_003561, NP_003552, NR_133651, PLA2G10, SPLA2, XM_011522695, XM_011522696, XM_011522697, XM_011522698, XP_011520997, XP_011520998, XP_011520999, XP_011521000, phospholipase A2 group X, sPLA2-X

Omim:OMIM:603603

Id:ENSG00000069764

Hgnc:HGNC:9029

Entrez:8399

Ensembl:ENSG00000069764

Description:phospholipase A2 group X

This gene encodes a member of the phospholipase A2 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This calcium-dependent enzyme hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids. In one example, this enzyme catalyzes the release of arachidonic acid from cell membrane phospholipids, thus playing a role in the production of various inflammatory lipid mediators, such as prostaglandins. The encoded protein may promote the survival of breast cancer cells through its role in lipid metabolism. [provided by RefSeq, Nov 2015]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PLA2G10's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PLA2G10.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PLA2G10.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PLA2G10.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PLA2G10.

Results found

Linked to

	Label	Description
	T61-Colon Consensus Gene Set (Entity type)	A Gene Set from MoTrPAC
	GSE74251 decitabine MCF-7 2 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE80802 EGFR inhibition Tankyrases 0 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE74251 2 V 3 DECITABINE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE74251 decitabine MCF-7 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE108464 AZ-628 1 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE178292 melphalan 0 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE116810 5 V 1 SELINEXOR HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE171175,GSE171181 1 V 0 E7107 HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE74251 0 V 1 DECITABINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS

T61-Colon Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

GSE74251 decitabine MCF-7 2 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE80802 EGFR inhibition Tankyrases 0 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE74251 2 V 3 DECITABINE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE74251 decitabine MCF-7 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE108464 AZ-628 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE178292 melphalan 0 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE116810 5 V 1 SELINEXOR HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE171175,GSE171181 1 V 0 E7107 HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE74251 0 V 1 DECITABINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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