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Data Matrix

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CFTR (Gene)

Ensembl Gene ID: ENSG00000001626

Entrez Gene ID: 1080

Description: CF transmembrane conductance regulator

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CFTR's neighborhood in the knowledge graph.

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CFTR.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CFTR.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CFTR.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CFTR.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

This repository is under review for potential modification in compliance with Administration directives.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	KU-C104142 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CFTR Gene (Entity type)	0.011800706
	1-phenylbiguanide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFTR Gene (Entity type)	-0.014351629
	4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFTR Gene (Entity type)	-0.008713304
	KFGENEBIN:CFTR-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	CFTR Gene (Entity type)
	TUL-XX023 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CFTR Gene (Entity type)	0.009160801
	MW-STK33-100 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CFTR Gene (Entity type)	0.013877009

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