S100A8 (Gene)

Description: S100 calcium binding protein A8

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View S100A8's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with S100A8.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using S100A8.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for S100A8.

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Gene Sets (5612)

LINCS L1000 Chem Pert Consensus Sigs (2702)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (5)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (2877)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (19)

A gene set library provided by GTEx

GTEx Tissues V8 2023 (9)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
(5-chloro-1H-benzo[d]imidazol-2-yl)(4-methylpiperazin-1-yl)methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	-0.013292749
Dantrolene Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	-0.0047397087
Talampanel Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	0.005519387
tienilic-acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	0.0117938435
AMG-073::AMG073 HCL::CINACALCET::CINACALCET HYDROCHLORIDE::US9487494, Cinacalcet Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	-0.006078008
8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-ylamino)-ethyl]-1H-quinolin-2-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	0.0038418218
2-[(diphenylmethyl)sulfinyl]acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	-0.010642867
Galanthamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	0.0050563957
huperzine-a Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	0.0048071644
mirtazapine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	0.004705176