TYRP1 (Gene)

Description: tyrosinase related protein 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TYRP1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TYRP1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TYRP1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TYRP1.

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Gene Sets (2159)

LINCS L1000 Chem Pert Consensus Sigs (1117)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (1021)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (17)

A gene set library provided by GTEx

GTEx Tissues V8 2023 (2)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Buphenine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TYRP1 Gene (Entity type)	-0.008482658
TYRP1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	5,6-Indolequinone-2-carboxylic acid Metabolite (Entity type)
KDM-096 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TYRP1 Gene (Entity type)	-0.013396785
mavorixafor Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TYRP1 Gene (Entity type)	0.0030076555
Melperone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TYRP1 Gene (Entity type)	0.00441957
Propylthiouracil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TYRP1 Gene (Entity type)	0.0052904696
2H-chromen-2-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TYRP1 Gene (Entity type)	0.008296177
isorotenone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TYRP1 Gene (Entity type)	0.0075316867
ribavirin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TYRP1 Gene (Entity type)	-0.0031193974
JAS07-006 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TYRP1 Gene (Entity type)	-0.014621011