CASP2 (Gene)

Description: caspase 2

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CASP2's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CASP2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CASP2.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CASP2.

Submit

Gene Sets (2296)

LINCS L1000 Chem Pert Consensus Sigs (1097)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (5)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (11)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (1183)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
meticrane Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CASP2 Gene (Entity type)	-0.008923807
ceforanide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CASP2 Gene (Entity type)	-0.0073936437
K-145 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CASP2 Gene (Entity type)	0.006133741
EMF-sumo1-1 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CASP2 Gene (Entity type)	0.008305217
SQ-29548 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CASP2 Gene (Entity type)	0.010616232
dipyridamole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CASP2 Gene (Entity type)	0.006939476
N-{5-methoxy-6-methyl-18-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl}-N-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CASP2 Gene (Entity type)	-0.004240978
RAN-14A Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CASP2 Gene (Entity type)	0.00886099
(R)-N-(7-chloro-1-(1-(4-(dimethylamino)but-2-enoyl)azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CASP2 Gene (Entity type)	-0.019667976
N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CASP2 Gene (Entity type)	-0.00379468