HES1 (Gene)

Description: hes family bHLH transcription factor 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HES1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HES1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HES1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HES1.

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Gene Sets (606)

LINCS L1000 Chem Pert Consensus Sigs (480)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (124)

A gene set library provided by LINCS

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HES1 Gene (Entity type)	0.0046971543
Propionic acid 6,9-difluoro-17-fluoromethylsulfanylcarbonyl-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl ester (Fluticasone Propionate, FP) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HES1 Gene (Entity type)	-0.006100945
2-methyl-6-(phenylethynyl)pyridine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HES1 Gene (Entity type)	-0.004910876
Diacerein Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HES1 Gene (Entity type)	0.0040961285
radicicol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HES1 Gene (Entity type)	-0.009095489
Narciclasine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HES1 Gene (Entity type)	0.029236412
batimastat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HES1 Gene (Entity type)	-0.0053220033
UCN-01 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HES1 Gene (Entity type)	-0.009902288
KFGENEBIN:HES1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	HES1 Gene (Entity type)
epothilone-a Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HES1 Gene (Entity type)	-0.013706457