HK2 (Gene)

Description: hexokinase 2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HK2's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HK2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HK2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HK2.

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Gene Sets (1454)

LINCS L1000 Chem Pert Consensus Sigs (792)

A gene set library provided by LINCS

LINCS L1000 CRISPR KO Consensus Sigs (648)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (5)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (8)

A gene set library provided by MoTrPAC

IDG Drug Targets 2022 (1)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
HK2 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	atp binding Metabolite (Entity type)
Benzofuran-2-carboxylic acid (2-{4-[benzyl-(2-hydroxycarbamoyl-4,6-dimethyl-phenyl)-sulfamoyl]-phenoxy}-ethyl)-amide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HK2 Gene (Entity type)	0.011151927
Tozadenant Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HK2 Gene (Entity type)	0.004671678
N-(4-acetyl-5-methyl-5-phenyl-4,5-dihydro-1,3,4-thiadiazol-2-yl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HK2 Gene (Entity type)	-0.008404476
SU-1498 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HK2 Gene (Entity type)	0.010302468
GSK-1838705A Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HK2 Gene (Entity type)	0.0061593656
Alectinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HK2 Gene (Entity type)	0.0037912154
SID11114248 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HK2 Gene (Entity type)	-0.010097163
HK2 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	glucosamine Metabolite (Entity type)
N,N'-(1,3-phenylene)bis(2,3-dihydroxybenzamide) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HK2 Gene (Entity type)	0.008946584