IER3 (Gene)

Description: immediate early response 3

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View IER3's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with IER3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using IER3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for IER3.

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Gene Sets (1080)

LINCS L1000 Chem Pert Consensus Sigs (816)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (258)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (1)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
tubacin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IER3 Gene (Entity type)	0.017558316
sulfanitran Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IER3 Gene (Entity type)	-0.04833625
Clobetasol propionate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IER3 Gene (Entity type)	-0.010610943
linsitinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IER3 Gene (Entity type)	0.0039595766
Lestaurtinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IER3 Gene (Entity type)	-0.011273815
proscillaridin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IER3 Gene (Entity type)	0.01700767
SID856008 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IER3 Gene (Entity type)	-0.0029609767
5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IER3 Gene (Entity type)	-0.033062004
PD-198306 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IER3 Gene (Entity type)	-0.01350876
gitoxigenin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IER3 Gene (Entity type)	0.0118796285