STAT3 (Gene)

Description: signal transducer and activator of transcription 3

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View STAT3's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with STAT3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using STAT3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for STAT3.

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Gene Sets (767)

LINCS L1000 Chem Pert Consensus Sigs (233)

A gene set library provided by LINCS

GlyGen Glycosylated Proteins 2022 (1)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (529)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

IDG Drug Targets 2022 (3)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SA-1456734 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	STAT3 Gene (Entity type)	0.017404549
Dasabuvir Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	STAT3 Gene (Entity type)	-0.0040522334
Alvelestat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	STAT3 Gene (Entity type)	-0.003748351
1-(1-(3-(Methylsulfonyl)-phenyl)-7-propoxyindolizin-3-yl)ethanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	STAT3 Gene (Entity type)	0.023496782
1-(2-Chloro-thiophen-3-yl)-2-(2,4-dichloro-phenyl)-3-imidazol-1-yl-propan-2-ol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	STAT3 Gene (Entity type)	-0.0047597676
Atovaquone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	STAT3 Gene (Entity type)	0.005002353
Barasertib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	STAT3 Gene (Entity type)	0.004668768
Gaboxadol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	STAT3 Gene (Entity type)	0.005142927
Doxapram Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	STAT3 Gene (Entity type)	-0.0028936402
SA-432998 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	STAT3 Gene (Entity type)	0.009296517