PLK2 (Gene)

Description: polo like kinase 2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PLK2's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PLK2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PLK2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PLK2.

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Gene Sets (2944)

LINCS L1000 Chem Pert Consensus Sigs (1395)

A gene set library provided by LINCS

LINCS L1000 CRISPR KO Consensus Sigs (1543)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

IDG Drug Targets 2022 (4)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Finasteride Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLK2 Gene (Entity type)	-0.0033094406
Propionic acid 6,9-difluoro-17-fluoromethylsulfanylcarbonyl-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl ester (Fluticasone Propionate, FP) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLK2 Gene (Entity type)	-0.005899872
dimethyl-fumarate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLK2 Gene (Entity type)	0.005034646
SA-1457187 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLK2 Gene (Entity type)	-0.010677045
N-(4-acetyl-5-methyl-5-phenyl-4,5-dihydro-1,3,4-thiadiazol-2-yl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLK2 Gene (Entity type)	0.010286689
SA-1919710 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLK2 Gene (Entity type)	-0.015056748
tert-butylhydroquinone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLK2 Gene (Entity type)	-0.0040117395
STK-222600 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLK2 Gene (Entity type)	0.0049108984
ioxaglic-acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLK2 Gene (Entity type)	0.008683992
Taurocholic-acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLK2 Gene (Entity type)	0.0076951943