PRUNE2 (Gene)

Description: prune homolog 2 with BCH domain

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PRUNE2's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PRUNE2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PRUNE2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PRUNE2.

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Gene Sets (2225)

LINCS L1000 Chem Pert Consensus Sigs (976)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (4)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (1215)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (14)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (15)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Methyl-(3-phenyl-3-o-tolyloxy-propyl)-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRUNE2 Gene (Entity type)	-0.0042981612
SA-1456625 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRUNE2 Gene (Entity type)	0.016888479
vardenafil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRUNE2 Gene (Entity type)	0.0039071157
Doxercalciferol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRUNE2 Gene (Entity type)	-0.011512414
sarmentogenin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRUNE2 Gene (Entity type)	-0.017139765
NU-1025 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRUNE2 Gene (Entity type)	-0.0085521825
KU-C103443N Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRUNE2 Gene (Entity type)	0.013138496
Tipiracil Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRUNE2 Gene (Entity type)	-0.005300553
chlorphensin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRUNE2 Gene (Entity type)	0.009541643
Guanadrel Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRUNE2 Gene (Entity type)	0.00273778