1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea (Compound)

Pubchem:PUBCHEM:24889392

Id:eebd5be4-c3de-518c-a696-5a0f6e0c7dfc

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea's neighborhood in the knowledge graph.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for 1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with 1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea.

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	Label	Description
	1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea positively regulates IFI16 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea indication Acute myeloid leukemia with FMS-like tyrosine kinase-3 mutation Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from IDG
	1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea bioactivity Myosin-10 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from IDG
	1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea negatively regulates CADM1 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea positively regulates IFI6 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea negatively regulates ITM2A Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea positively regulates DUSP6 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea bioactivity Receptor-type tyrosine-protein kinase FLT3 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from IDG
	1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea negatively regulates TXNIP Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea negatively regulates AKAP7 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS

1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea positively regulates IFI16

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from LINCS

1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea indication Acute myeloid leukemia with FMS-like tyrosine kinase-3 mutation

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from IDG

1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea bioactivity Myosin-10

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from IDG

1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea negatively regulates CADM1

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from LINCS

1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea positively regulates IFI6

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from LINCS

1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea negatively regulates ITM2A

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from LINCS

1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea positively regulates DUSP6

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from LINCS

1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea bioactivity Receptor-type tyrosine-protein kinase FLT3

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from IDG

1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea negatively regulates TXNIP

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from LINCS

1-(5-tert-Butyl-isoxazol-3-yl)-3-{4-[7-(2-morpholin-4-yl-ethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl]-phenyl}-urea negatively regulates AKAP7

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from LINCS

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CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

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