2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid (Compound)

Synonyms:1352066-68-2, AMG-232, AMG 232, AMG232, Navtemadlin, KRT-232, Mdm2 inhibitor amg-232, 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid, Navtemadlin [USAN], 7R7G6EH5UL, CHEMBL3125702, 2-[(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-1-[(2S)-3-methyl-1-propan-2-ylsulfonylbutan-2-yl]-2-oxopiperidin-3-yl]acetic acid, NAVTEMADLIN [INN], UNII-7R7G6EH5UL, KRT232, SCHEMBL9993310, AMG 232 [WHO-DD], GTPL11133, DTXSID101025652, BDBM50448947, NSC781515, NSC789723, WHO 11546, compound 2 [PMID: 24456472], CS-3282, DB15299, NSC-781515, NSC-789723, NCGC00387801-04, NCGC00387801-05, AC-29027, AS-17007, HY-12296, A910091, (3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-3-methyl-1-((1S)-2-methyl-1-(((1-methylethyl)sulfonyl)methyl)propyl)-2-oxo-3-piperidineacetic acid, {(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3- methyl-1-[(2S)-3-methyl-1-(propane-2-sulfonyl)butan2-yl]-2-oxopiperidin-3-yl}acetic acid, 1447813-21-9, 3-iperidineacetic acid, 5-(3-hlorophenyl)-6-(4-hlorophenyl)-3-ethyl-1-(1S)-2-ethyl-1-[(1-ethylethyl)ulfonyl]ethyl]ropyl]-2-xo-, (3R,5R,6S)-, 3-Piperidineacetic acid, 5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-1-[(1S)-2-methyl-1-[[(1-methylethyl)sulfonyl]methyl]propyl]-2-oxo-, (3R,5R,6S)-

Pubchem:PUBCHEM:58573469

Id:80d07a80-c487-5b5d-b2bd-8ed58441b39d

Description:nan

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid's neighborhood in the knowledge graph.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid.

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Results found

Linked to

	Label	Description
	BRD-K64925568-001-01-8 Substance (Entity type)	A Substance
	amg-232 (07caa495-8992-4b73-92df-76fc0554c0a5) Collection (Entity type)	Metadatata for amg-232
	2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid negatively regulates PBK Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid positively regulates RPS27L Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid positively regulates ZMAT3 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid positively regulates FDXR Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid negatively regulates HOXC6 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	Palbociclib; Ibrance in similarity relationship with 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	Nutlin-2 in similarity relationship with 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid positively regulates EREG Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS

BRD-K64925568-001-01-8

Substance (Entity type)

A Substance

amg-232 (07caa495-8992-4b73-92df-76fc0554c0a5)

Collection (Entity type)

Metadatata for amg-232

2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid negatively regulates PBK

Knowledge Graph Assertion (Entity type)