LINCS

The Common Fund’s Library of Integrated Network-based Cellular Signatures (LINCS) program developed a library that catalogs changes that occur when different types of cells are exposed to a variety of agents that disrupt normal cellular functions, called “perturbagens.” This libr...read more

Metadata and Processed Data Files

Current
FilenameCreatorFilesizeDate ModifiedDCC ApprovedDRC Approved
datapackage.zipLINCS169.2 Mb9/18/2023
Archived
FilenameCreatorFilesizeDate ModifiedDCC ApprovedDRC Approved
datapackage.zipLINCS166.0 Mb6/15/2023
datapackage.zipLINCS166.7 Mb3/21/2023
datapackage.zipLINCS166.2 Mb12/2/2022
datapackage.zipLINCS165.5 Mb9/14/2022
datapackage.zipLINCS164.2 Mb6/20/2022
datapackage.zipLINCS171.1 Mb4/14/2022
datapackage.zipLINCS171.1 Mb1/11/2022
datapackage.zipLINCS131.1 Mb9/29/2021
datapackage.zipLINCS141.3 Mb6/2/2021
datapackage.zipLINCS28.1 Mb3/24/2021
Current
FilenameCreatorFilesizeDate ModifiedDCC ApprovedDRC Approved
LINCS_L1000_CRISPR_KO_Consensus_Sigs.gmtDRC14.9 Mb12/13/2022
LINCS_L1000_Chem_Pert_Consensus_Sigs.gmtDRC15.6 Mb12/13/2022
Archived
FilenameCreatorFilesizeDate ModifiedDCC ApprovedDRC Approved
LINCS_L1000_Ligand_Perturbations_up.gmtDRC87.4 Kb6/6/2022
LINCS_L1000_Chem_Pert_up.gmtDRC15.5 Mb6/6/2022
LINCS_L1000_Ligand_Perturbations_down.gmtDRC93.0 Kb6/6/2022
LINCS_L1000_Chem_Pert_down.gmtDRC13.4 Mb6/6/2022
Current
FilenameCreatorFilesizeDate ModifiedDCC ApprovedDRC Approved
LINCS_L1000_CRISPR_KO_Perturbation_Consensus_CD_Sigs.h5DRC317.5 Mb3/29/2024
LINCS_L1000_Chemical_Perturbation_Consensus_CD_Sigs.h5DRC1.4 Gb3/28/2024
Archived

None Available

Current
FilenameCreatorFilesizeDate ModifiedDCC ApprovedDRC Approved
LINCS.zipDRC11.6 Mb5/8/2024
Archived
FilenameCreatorFilesizeDate ModifiedDCC ApprovedDRC Approved
LINCS.edges.csvDRC54.6 Mb10/26/2023

Interoperability Assets

Current
NameCreatorDate ModifiedDCC ApprovedDRC Approved
build_file_lincs2021.pyDRC6/23/2021
process_mcf10a_c2m2.pyDRC5/22/2022
Archived

None Available

Current
NameCreatorDate ModifiedDCC ApprovedDRC Approved

Enrichr (SmartAPI)

DRC1/31/2023

FAIRshake API v2 (SmartAPI)

DRC4/5/2022

Harmonizome (SmartAPI)

DRC1/31/2023

L1000CDS2 (SmartAPI)

DRC1/31/2023

L1000FWD (SmartAPI)

DRC1/31/2023

SigCom LINCS Data (SmartAPI)

DRC5/22/2022

SigCom LINCS Metadata (SmartAPI)

DRC5/22/2022
Archived
NameCreatorDate ModifiedDCC ApprovedDRC Approved

FAIRshake (SmartAPI)

DRC8/7/2018
Current
NameCreatorDate ModifiedDCC ApprovedDRC Approved

Drugmonizome Drug Pages
Template | Example

DRC3/8/2024

Harmonizome Gene Pages
Template | Example

DRC3/8/2024

SigCom LINCS Drug Pages
Template | Example

DRC3/8/2024

SigCom LINCS Gene Pages
Template | Example

DRC3/8/2024
Archived

None Available

Current
NameCreatorDate ModifiedDCC ApprovedDRC Approved
LINCS L1000 Reverse SearchDRC7/19/2023
SigCom LINCS Gene Set Search ResultsDRC2/7/2024
SigCom LINCS Signature Search ResultsDRC2/7/2024
Archived
NameCreatorDate ModifiedDCC ApprovedDRC Approved
LINCS L1000 Reverse SearchDRC2/26/2024
Current

None Available

Archived

None Available

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